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EINECS
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ERYTHROPOIETIN , Human , recombinant , CHO Cells
EPO , Erythropoietin-α
100% made in European Union *(according to USP, EUP, Echa-Reach)
>99.99+% (1st. quality virgin matter , extra pure, selected )
Lab. / Pharmaceutical / Medicine / API & Intermediates
EM1817
11096-26-7
MFCD00131025
234-317-2
In 300 mM NaCl, 20 mM Na/K phosphate, pH 7.5.
KF5885000
Endotoxin: <10 EU/10 µg protein
≥1.0 X 10⁵ IU/mg protein
reconstitute with 500 µl H₂O or aqueous buffer
-20 °C
OK to freeze
>99.99 % ( typical NLT )
standard handling
following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C or
-70°C) for long-term storage; stock solutions are stable for up to 1 month at 4 °C , up to 3
months at -20 °C , or up to 6 months at -70 °C ; avoid freeze/thaw cycles of solutions .
clear , colourless
liquid
recombinant, human erythropoietin (EPO) expressed in CHO cells. EPO is a glycoprotein hormone produced by the kidneys that is involved in the survival , growth , and differentiation of erythroid precursor cells ; stimulation of erythropoiesis involves the binding of EPO to the extracellular
domain of the EPO receptor ( EPOR ) and triggering of intracellular signaling events , including phosphorylation of the receptor and activation of the JAK-STAT, RAS, and PI3-kinase pathways . Reported to act as a neuroprotective agent ; expressed in and purified from CHO cells ; The
predicted molecular weight is ~21 kDa , but it migrates at ~37 kDa on SDS-PAGE ; Sialic acid
content: > 10 moles/mole of protein. Sialic acid content: > 10 moles/mole of protein .
Erythropoietin, or EPO , is a glycoprotein hormone that controls erythropoiesis , or red blood cell production; it is a cytokine for erythrocyte (red blood cell) precursors in the bone marrow .
Also called hematopoietin or hemopoietin, it is produced by the peritubular capillary endothelial
cells in the kidney, and is the hormone that regulates red blood cell production; it also has other known biological functions. For example, erythropoietin plays an important role in the brain's
response to neuronal injury; EPO is also involved in the wound healing process; when exogenous
EPO is used as a performance-enhancing drug , it is classified as an erythropoiesis-stimulating
agent (ESA) ; exogenous EPO can often be detected in blood , due to slight difference from the endogenous protein, for example in features of posttranslational modification .
according to government transport (IATA, ADR) rules
special for chemicals transport
C.O.A., MSDS, GMP, API, USP, EUP, ECHA-REACH, ORIGIN, etc...
(originals will be delivered with good , and copies after confirmed order )
the price of the product is NO NEGOTIABLE , already around 25% lower than the official price of
the International Chemical Stock Exchange / ICIS |
